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General Information

Erowid - "Documenting the complex relationship between humans and psychoactives."
Opioids : Past, Present and Future - Most extensive guide on the Internet.
Poppies.org - "The continuing adventures of the world's most controversial flower."

General Pharmaceutical Information

Drugs.com - Searchable comprehensive guide for consumers and professionals of over 24,000 drugs.
RxList.com - Searchable drug index for both consumers and professionals.

Pharmaceuticals

Suboxone - Company site for Suboxone, an opiate dependency treatment drug (Prescribing info., treatment education, etc.)

Forums

Bluelight - Promotes responsible drug use via open discussion.
DanceSafe - Promotes safety within the rave and nightclub community with one focus being drug safety.
Detox Forum, The - Provides support for detoxing off of maintenence drugs.
Opiate Detox and Recovery - Opiate addiction support group.
Opiophile.org - Opioid-specific forums, and related news.

Addiction Treatment/Programs

Methadone Anonymous - Support via forums and licensed doctor for those trying to get off methadone.
Narcotics Anonymous - International, community-based, and religion-oriented association of recovering drug addicts.
SMART Recovery - Self-management and recovery training for all types of addiction. Based on scientific knowledge, logic, etc.